Acomplia (Zimulti) Acomplia is used to treat overweight patients. It works by blocking certain brain receptors and fat tissues called CB1 receptors Drug use Buy Acomplia is used for weight loss, can also be used to treat overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood. It works by blocking certain brain receptors and fat tissues called CB1 receptors. Use Acomplia together with lower calorie diet and exercise. Acomplia also ...